Hyperinsulinemia and Autonomic Nervous System Dysfunction in Obesity

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Hyperinsulinemia and autonomic nervous system dysfunction in obesity: effects of weight loss.

BACKGROUND Because hyperinsulinemia acutely stimulates adrenergic activity, it has been postulated that chronic hyperinsulinemia may lead to enhanced sympathetic tone and cardiovascular risk. METHODS AND RESULTS In 21 obese (body mass index, 35+/-1 kg/m(2)) and 17 lean subjects, we measured resting cardiac output (by 2-dimensional echocardiography), plasma concentrations and timed (diurnal ve...

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Autonomic Nervous System Dysfunction in Parkinson's Disease.

Autonomic nervous system (ANS) dysfunction is common in Parkinson's disease (PD), affects 70% to 80% of patients, and causes significant morbidity and discomfort. Autonomic nervous system dysfunction symptoms in PD include sexual dysfunction, swallowing and gastrointestinal disorders, bowel and bladder abnormalities, sleep disturbances, and derangements of cardiovascular regulation, particularl...

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Effect of obesity on autonomic nervous system

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Autonomic nervous system dysfunction in sclerodermic and primary Raynaud's phenomenon.

Our aim was to investigate the sympathetic hyperactivity of systemic sclerosis that may lead to greater morbidity and mortality from cardiovascular events. We analysed the sympathetic (low-frequency) and vagal (high-frequency) components of heart rate variability, in supine and upright positions, in 10 patients with systemic sclerosis, 12 patients with primary Raynaud's phenomenon and 14 contro...

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Dysfunction of Autonomic Nervous System in Childhood Obesity: A Cross-Sectional Study

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ژورنال

عنوان ژورنال: Circulation

سال: 2001

ISSN: 0009-7322,1524-4539

DOI: 10.1161/01.cir.103.4.513